Trimetazidine
Trimetazidine is described as the first cytoprotective anti-ischemic agent developed and marketed by Laboratoires Servier France. The pH-partition profile of the anti-ischemic drug trimetazidine may explain its reduction of intracellular acidosis.
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Trimetazidine is used in combination with other drugs for the symptomatic treatment of stable angina pectoris chest pain caused by decreased oxygen supply due to reduced blood flow to the heart.
. This medicine also prevents a sudden rise in blood pressure and also helps in reducing the frequency of angina attacks. By preserving energy metabolism in cells exposed to ischaemia or hypoxia it prevents decrease in intracellular ATP levels and ensures proper functioning of ionic pumps and transmembrane Na-K flow. Russian media reported that.
11 hours agoTrimetazidine also known as TMZ is a drug used to treat the heart condition angina so it might seem strange that its also considered a banned substance by the World Anti-Doping Association. Trimetazidine is an anti-anginal medication. Common side effects of Trimetazidine Dizziness Headache Nausea Vomiting Weakness Rash Abdominal pain Indigestion Itching Diarrhea Hives.
11 hours agoTrimetazidine is a fatty acid oxidation inhibitor used to prevent and treat the symptoms of angina or chest pain that is the result of a lack of blood supply and oxygen to the heart. Trimetazidine is used for the treatment of chest tightness medically known as angina pectoris. This medicine is used when patients do not respond adequately to other agents or are intolerant to first line anti-anginal agents.
An angina drug called trimetazidine has been in the news lately connected to the 2022 Winter Olympics but its been on the radar of anti-doping authorities for years. It decreases the oxygen requirement of the heart by shifting its metabolism from fats to glucose. 16 hours agoTrimetazidine also known as TMZ is a heart medication banned in international sports like the Winter Olympics for years Published 9 seconds ago Leon Neal An angina drug called trimetazidine has.
As a result the heart works more efficiently. Trimetazidine inhibits β-oxidation of fatty acids by blocking long-chain 3-ketoacyl-CoA thiolase thereby enhancing glucose oxidation. It works by producing a good supply of.
Trimetazidine is an anti-ischemic anti-anginal metabolic agent of the fatty acid oxidation inhibitor class meaning that it improves myocardial glucose utilization through inhibition of fatty acid metabolism.
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